and the take on and the at Oriole Park at Camden Yards on Thursday at 7:08 p.m. ET, in the first game of a four-game series. The Astros are listed as +135 moneyline underdogs in this matchup against the favored Orioles (-159). Baltimore is a 1.5-run favorite (at +130 odds). A 7.5-run over/under has been listed for the matchup. Here's everything you need from a betting perspective on the Orioles-Astros game, regarding the run line, moneyline and total, plus expert picks. Eric Karros' Top 5 World Series Contenders for the MLB 2024 Season Orioles vs. Astros Game Information & Odds When: Thursday, August 22, 2024 at 7:08 p.m. ET Where: Oriole Park at Camden Yards in Baltimore, Maryland How to Watch on TV: FOX Favorite Favorite Moneyline Underdog Moneyline Total Over Total Odds Under Total Odds Run Line Favorite Run Line Odds Underdog Run Line Odds Orioles -159 +135 7.5 -113 -107 -1.5 +130 -155 Orioles vs. Astros Prediction Score Prediction: Orioles 5, Astros 4 Total Prediction: Over 7.5 runs Win Probabilities: Orioles 53%, Astros 47% Orioles vs. Astros Betting Insights The Orioles have won 58, or 59.8%, of the 97 games they've played as favorites this season. This season Baltimore has won 26 of its 41 games, or 63.4%, when favored by at least -159 on the moneyline. The implied probability of a win from the Orioles, based on the moneyline, is 61.4%. The Astros have been victorious in 16, or 48.5%, of the 33 contests they have been chosen as underdogs in this season. Houston has played as an underdog of +135 or more just one time this year and came away with a lo s in that game. Edwin Rios Jersey The moneyline set for this matchup implies the Astros have a 42.6% chance of coming away with a victory in the contest. Orioles Recent Betting Performance The Orioles were the moneyline favorite for six of their last 10 games, and went 4-2 in those matchups. In their last 10 outings, the Orioles and their opponents combined to go over the run total four times (all 10 of the games had set totals). The Orioles are 7-3-0 against the spread over their past 10 games. Orioles Recent Stats Stat Avg/Total Record 4-6 Runs Per Game 4.3 HR 13 ERA 4.55 K/9 9 Orioles Player Insights Henderson's .287 average leads the Orioles this year. His resume also includes 33 homers and driven in 78 RBI. Henderson's home runs place him sixth in MLB, and he is 19th in RBI. Henderson has collected a hit in two games in a row. In his last five games he is batting .278 with two home runs, three walks and four RBI. has hit 37 home runs with 82 RBI. Both pace his team. Santander is third in homers and 13th in RBI among all MLB batters this season. has 16 doubles, a triple, 18 home runs and 44 walks while hitting .262. Ryan O'Hearn is batting .275 with 15 doubles, three triples, 12 home runs and 40 walks. Orioles Team Props Hits O/U Total Bases O/U HR O/U RBI O/U Anthony Santander 0.5 (-195) 1.5 () - 0.5 (+155) 0.5 (-200) 1.5 () - 0.5 (+190) Gunnar Henderson 0.5 (-255) 1.5 (+115) - 0.5 (+165) 0.5 (-285) 1.5 (+110) - 0.5 (+145) Ryan O'Hearn 0.5 (-220) 1.5 (+125) - 0.5 (+155) Astros Recent Betting Performance The Astros are not favored for the first time in a while, as they have not been underdogs in their last 10 games. In their last 10 games with a total, the Astros and their opponents are 4-6-0 when it comes to hitting the over. The Astros have a record of 5-5-0 ATS over their last 10 games. Astros Recent Stats Stat Avg/Total Record 7-3 Runs Per Game 4.4 HR 16 ERA 2.27 K/9 10 Astros Player Insights Alvarez has recorded a team- leading batting average of .307, and leads the Astros in long balls with 25. Alvarez ranks 19th in homers and 40th in RBI among all hitters in the big leagues. has 25 doubles, two triples, 20 home runs and 36 walks while hitting .261. Bregman ranks 36th in home runs and 59th in RBI among all hitters in MLB. has 22 doubles, 16 home runs and 36 walks while batting .300. has driven in the most runs for the Astros with 71 runs batted in. Astros Team Props Hits O/U Total Bases O/U HR O/U RBI O/U 0.5 (-245) 1.5 (+145) - 0.5 (+185) Yainer Diaz 1.5 (+175) 1.5 (+115) - 0.5 (+150) Yordan Alvarez 0.5 (-240) 1.5 (+120) - 0.5 (+155) Jose Altuve 0.5 (-245) 1.5 (+130) - 0.5 (+220) Alex Bregman 0.5 (-260) 1.5 (+125) - 0.5 (+190) Eric Karros' Top 5 World Series Contenders for the MLB 2024 Season Jody Davis Jersey